How can i do multiple values filter for multiple fields in Django?

for loc,deg,dept,key,job_role,insti_loc,insti_name,mark,gen,job_type in zip(lst2,lst5,lst6,lst1,lst4,lst8,lst9,lst10,lst11,lst12):

        if sample_register.objects.filter(city=loc,job_role_1=job_role,qualification=deg,qualification_dept=dept).exists():
            print("Inside location and jobrole1 and qualification and department search")
            for i,j,k,l in zip(lst5,lst2,lst6,lst4):
                pro_log=sample_register.objects.filter(Q(city=j) & Q(job_role_1=l) & Q(qualification=i) &  Q(qualification_dept=k))