How can i disable a checkbox depends on datetimepicker in VB .Net?

On VB .NET is there any way to disable a checkbox, and if there are any date time picker is selected.

When I say select a date using date time picker, the checkbox still can't disabled.

The checkbox has been checked before on the date specified, and if I choose the same date as the

checkbox that I have checked the checkbox is still enabled, how can i disable that?, can you help me?