Change Checkbox in Javascript

how I can change this CheckBox in javascript? Checkboxes doesnt have Id or something :/

<ul class="DirectionFilter__filterlist__288E1AGnOl">

<li>
<label>
<input type="checkbox">Eingehend
</label>
</li>

<li>
<label>
<input type="checkbox" checked="">Ausgehend
</label>
</li>

</ul>

Thanks Guys.