C# MySql ChangeDatagGridView Information? Boolean

I have wrote a simple program that populates a datagrid from mysql.

In one of my columns I have a Boolean (0 or 1)

Once the datagrid populates with the query I have check boxes for the boolean.

Does anyone know how to use a function when you check the check boxes for the boolean? (This is to send an update of just the boolean of the column.)

The reason I am having an issue with this is simply because the datagrid does not populate until I run the application. Therefor I cannot figure out how to change it while in visual studio.

Any Help would be greatful.